Course Information
Course title
 Experimental Pharmacology (2) 
Semester
 103-2 
Designated for
 COLLEGE OF MEDICINE  GRADUATE INSTITUTE OF PHARMACOLOGY  
Instructor
 TUR FU HUANG 
Curriculum Number
 Phmco7004 
Curriculum Identity Number
 443 M1132 
Class
  
Credits
 3 
Full/Half
Yr.
 Full 
Required/
Elective
 Required 
Time
 Tuesday 2,3,4(9:10~12:10) 
Remarks
 The upper limit of the number of students: 30. 
Ceiba Web Server
 http://ceiba.ntu.edu.tw/1032Phmco7004_ 
Course introduction video
 
Table of Core Capabilities and Curriculum Planning
 Table of Core Capabilities and Curriculum Planning
Course Syllabus
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Course Description

上課內容著重於心血管、神經及幹細胞藥理學;主題如下：(1)血小板功能、血液凝固、細胞膜醣蛋白、Integrin受體、細胞附著、血管新生、癌細胞轉移、蛇毒與中草藥對血小板之影響、心血管疾病藥物之開發等。(2)幹細胞之簡介、幹細胞研究法、幹細胞在致病機制中之角色、幹細胞與藥物篩檢。(3)電氣生理和技術、中樞行為動物模式。(4)分子生物技術及藥物基因學。
 

Course Objective
 本課程著重在進行藥理分析之相關實驗技術之闡述，藉由本課程學生可以瞭解在心血管、癌症、中樞神經、骨質代謝、幹細胞等的實驗技術。包括細胞及動物實驗模式、有利於藥物開發、藥物基因學及藥物篩檢之研發。 
Course Requirement
 綜合下列三種方式評分:期末筆試、平時討論之表現、讀書報告。
 
Student Workload (expected study time outside of class per week)
  
Office Hours
  
Designated reading
 待補 
References
 待補 
Grading
    
Progress
Week
Date
Topic
第2週
 3/03  Stem Cell Biology (I)- Introduction and the methods for stem cells identification 
第3週
 3/10  Stem Cell Biology (II)- Stem cells and cell therapy and regulation 
第4週
 3/17  Stem Cell Biology (III)- Stem cells and tissue engineering 
第5週
 3/24  Animal behavior evaluation 
第6週
 3/31  Animal model for neuropharmacology 
第7週
 4/07  Bone metabolism 
第8週
 4/14  Receptor Biochemistry and Methodology 
第9週
 4/21  Adhesion molecules in arterial thrombosis, inflammation and tumor metastasis 
第10週
 4/28  Experimental methods in evaluating effects of drugs on platelet aggregation and angiogenesis 
第11週
 5/04  Genomic research toolkit: microarray and next-gen sequencing 
第12週
 5/11  Bioinformatic tools and resources for biomedical research 
第13週
 5/18  Primer on genetics and human diseases 
第14週
 5/26  細胞及分子生物學技術 (I)- Enzymes cloning, mutagesis, microRNA 
第15週
 6/02  細胞及分子生物學技術 (II)- Transgenic technology & Genome editing 
第16週
 6/09  細胞及分子生物學技術 (III)- Ab engineering